The Bone Marrow Microenvironment as Niche Retreats for Hematopoietic and Leukemic Stem Cells Figure 1: Organization of normal hematopoietic stem cell (HSC) and leukemic stem cell (LSC) niches in the bone marrow. Both HSCs and LSCs establish niches around the bone marrow endosteum and sinusoids. In normal hematopoiesis, the endosteal niche is ...
Leukemia - The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting Figure 1. (a) A model of bone marrow niches. In the marrow, osteoblasts and endothelial cells constitute the major cellular components contributing to the endosteal and vascular niches that serve as the microenvironment for maintaining hematopoietic stem
Bone-marrow haematopoietic-stem-cell niches : Article : Nature ... Adult stem cells are present in most self-renewing tissues, including the skin, the intestinal epithelium and the haematopoietic system. On a single-cell basis, ...
Osteoblastic cells regulate the haematopoietic stem cell niche - Nature Therefore, osteoblastic cells are a regulatory component of the haematopoietic stem cell niche in vivo that influences stem cell function through Notch activation.
Hematopoietic stem cell niche maintenance during homeostasis and ... 2014年8月6日 - The maintenance and proliferation of hematopoietic stem cells after injury is regulated by signals from the bone marrow stem cell niche.
The hematopoietic stem cell niche | StemBook The hematopoietic stem cell (HSC) niche is the anatomical location in which HSCs reside and self-renew. The HSCs outside the niche do not self-renew and ...
The hematopoietic stem cell and its niche: a comparative view Abstract. Stem cells have been identified as a source of virtually all highly differentiated cells that are replenished during the lifetime of an animal. The critical ...
The haematopoietic stem cell niche at a glance 2011年11月1日 - Haematopoietic stem cells (HSCs) regulate the balanced turnover of erythrocytes , platelets and all immune cells by switching between ...
Regulation of hematopoietic stem cells by bone marrow stromal ... 2013年11月6日 - Hematopoietic stem cells (HSCs) reside in specialized microenvironments ( niches) in the bone marrow. The stem cell niche is thought to ...
